class ii antigen是什么意思_class ii antigen中文

class ii antigen中文什么意思

《英文msh词典》Class II Antigen
[入口词] Class II Antigen
[主题词] Histocompatibility Antigens Class II
[英文释义] Large,transmembrane,non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice,two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes,macrophages,epidermal cells,and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse,but is now used as a generic term for any class II histocompatibility antigen.

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as c ii ta is a single gene or protein that affects a large family of genes, it represents an ideal target for intervention in the class ii antigen presentation pathway, for immune suppression in transplantation and autoimmumty
作为影响一个大基因家族的单个基因或蛋白质，cta是对mhc-类的抗原提呈过程进行干预的理想靶点，可以在自身免疫损伤和移植排异过程中进行免疫抑制干预。

class ii antigen中文什么意思